Poster 220 Superglue to the Rescue: Use of Cyanoacrylate Spray to Stop Bleeding From Large Peptic Ulcer

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    **EMBARGOED All research presented at the ACG Annual Scientific Meeting is strictly embargoed until Monday, October 19, 2015 at 8 AM (EDT).


    Poster 220 Superglue to the Rescue: Use of Cyanoacrylate Spray to Stop Bleeding From Large Peptic Ulcer 

    Author Insights from Siddharth Javia, MD; Nirav C. Thosani, MD, MHA, University of Texas Health Science Center at Houston

    What’s new here and important for clinicians?

    We report successful use of n-butyl-2-cyanoacrylate glue spray to control recurrent bleeding from a large peptic ulcer invading into muscularis propria, for which epinephrine injection, hemoclip application and thermal therapy were unsuccessful at controlling bleeding.

    What do patients need to know?

    Ulcer bleeding from stomach or small intestine could be a life-threatening condition. There are various endoscopic modalities of treatment to control bleeding, e.g. cautery, clip application, and epinephrine injection. Some ulcers are too deep and are at risk of perforation if extensive cauterization is performed. Clip application might be unsuccessful for ulcers that are too wide to close with a clip. Cyanoacrylate superglue spray may prove to be a new way to control bleeding from stomach ulcers that are difficult to treat with cautery or clip, and may help to avoid surgery or life-threatening events in such patients.

    Read the abstract

    Initial EGD Bleeding pyloric channel ulcer

    Initial EGD Pyloric channel ulcer with adherent clot

    Initial EGD adherent clot

    Initial EGD sp Epinephrine injection

    Initial EGD mechanical clot removal

    Initial EGD bipolar electrocoagulation

    Initial EGD sp control of bleeding

    Repeat EGD bleeding from pyloric channel ulcer

    Repeat EGD pyloric channel ulcer with fresh blood clot

    Repeat EGD sp bipolar electrocoagulation

    Repeat EGD unsuccessful clip application

    Repeat EGD sp 5 cc of glue spray on right side of ulcer

    Repeat EGD sp glue spray control of bleeding

    Authors Contact Siddharth Javia, MD; Nirav C. Thosani, MD, MHA, University of Texas Health Science Center at Houston

    sidbj00@gmail.com

    ncthosani@gmail.com.


    Media Interview Requests:

    To arrange an interview with any ACG experts or abstract authors please contact Jacqueline Gaulin of ACG via email jgaulin@gi.org or by phone at 301-263-9000.

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