Safety Outcomes After Fecal Microbiota Transplantation (FMT) For C. difficile Infection (CDI)

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    P939 Safety Outcomes After Fecal Microbiota Transplantation (FMT) For C. difficile Infection (CDI)

    Desmond Wilson, MD

    Desmond Wilson, MD

    Colleen Kelly, MD Alpert Medical School of Brown University Women?s Gastrointestinal Health Department of Women?s Health Women's Medicine Collaborative

    Colleen R. Kelly, MD, FACG

    Author insight from Desmond Wilson, MD and Colleen R. Kelly, MD, FACG, The Alpert Medical School of Brown University, Providence, RI

    What’s new here and important for clinicians?
    Our data suggests that adverse events related to fecal microbiota transplant (FMT) for C. difficile infections (CDI) typically manifest as gastrointestinal symptoms that are either transient or mild. Any significant adverse events were likely unrelated to FMT. There has not been a study to our knowledge which highlights the adverse outcomes in the non-immunocompromised patient.

    What do patients need to know?
    Prior evidence has suggested that FMT is efficacious for patient’s with refractory CDI. One area of obvious concern is safety associated with this procedure. From our data it appears that FMT is generally well tolerated and not associated with acquiring procedure-related infections or serious adverse outcomes.

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    Author Contact: Desmond Wilson, MD, The Alpert Medical School of Brown University, Providence, RI
    desmond.wilson@upenn.uphs.edu 

    Related Abstracts
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    P1639 Fecal Microbiota Transplant for Treatment of Refractory C. difficile Colitis: Long-Term Follow-Up of 58 Patients
    Oral 71 C. difficile Associated Risk of Death Score (CARDS): A Novel Risk Score to Predict Mortality Among Hospitalized Patients With C. difficile Infection
    P454 Outcomes of Fecal Microbiota Transplantation for Clostridium difficile Infection in Patients With Inflammatory Bowel Disease


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