Normalization of Liver-Related Laboratory Parameters in HCV Genotype 1-Infected Patients With Cirrhosis After Treatment With ABT -450/R/Ombitasvir, Dasabuvir and Ribavirin

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    Oral 5: Normalization of Liver-Related Laboratory Parameters in HCV Genotype 1-Infected Patients With Cirrhosis After Treatment With ABT-450/R/Ombitasvir, Dasabuvir and Ribavirin

    Greg Everson, MD

    Gregory T. Everson, MD

    Author insight from Gregory T. Everson, MD, University of Colorado Denver and Hospital, Aurora, CO

    What’s new here and important for clinicians?

    1. In patients with cirrhosis, clearing HCV is only one goal – the high rates of SVR in TURQUOISE II are encouraging that many more patients with cirrhosis can be cured of their chronic hepatitis C infection.
    2. However, in cirrhosis reversing hepatic impairment is another key, perhaps the key, endpoint – is SVR associated with reversal of hepatic impairment.
    3. The improvement in standard blood tests, suggests that the SVR with this Interferon-Free, All Oral regimen improves the liver.

    What do patients need to know?

    1. More patients with cirrhosis will be cured with this and other new therapies
    2. Early data suggests that their hepatic dysfunction may reverse after they achieve SVR with treatment

     

    Read the Abstract

     Author Contact
    Gregory T. Everson, MD, University of Colorado Denver and Hospital, Aurora, CO
    greg.everson@ucdenver.edu

    Related Abstracts

    Oral 4 SVR12 of 99% Achieved With a Ribavirin-Free Regiment of ABT-450r Ombitasvir and Dasabuvir in HCV Genotype 1b-Infected Patients


    Media Interview Requests:

    To arrange an interview with any ACG experts or abstract authors please contact Jacqueline Gaulin of ACG via email jgaulin@gi.org or by phone at 301-263-9000.

     

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